Citrulline malate is a compound made by combining the amino acid L-citrulline with malic acid. It’s commonly used in sports supplements due to its effects on blood flow, energy production and fatigue reduction. All are crucial for endurance athletes.
How It Helps With Endurance Sports:
1. Increases Nitric Oxide Production
L-citrulline boosts nitric oxide (NO) levels in the body by converting into L-arginine, which is a direct precursor to NO. Higher NO levels cause vasodilation (widening of blood vessels), which improves oxygen and nutrient delivery to muscles during long efforts.
2. Reduces Fatigue and Muscle Soreness
Studies show that citrulline malate can help reduce perceived fatigue and muscle soreness, especially in longer-duration or repeated efforts. This means athletes can maintain pace longer and recover faster between intense efforts.
3. Improves ATP Production
The malate part of citrulline malate plays a role in the Krebs cycle, helping produce more aerobic energy (ATP). This supports sustained energy during long runs or cycling sessions.
4. Buffers Ammonia and Lactic Acid Build-Up
It helps remove ammonia, a waste product that contributes to fatigue. This helps maintain muscle function during long or intense endurance efforts..



